Abstract: Ti-MSU molecular sieve catalysts were prepared by hydrothermal synthesis and impregnation method, respectively. The samples were characterized by TG, X-ray diffraction, N2 adsorption-desorption and FT-IR. The epoxidation performance for 1- butylene was studied. The results show that the Ti atom species are the catalyst active component and the activity of Ti-MSU catalyst with 5.5w% Ti by impregnated method is much higher than the hydrothermal one.