Abstract: The ex-situ regeneration of KF-848 hydrotreating catalyst was conducted in Jiangsu Kechuang Petrochemical Co. Ltd. and commercial application of the regenerated catalyst in refinery of Liaoyang Petrochemical Company，CNPC was introduced. The performance of the catalyst in pilot plant and in industrial unit shows that the regenerated catalyst has a high activity of hydrodesulfurization, hydrodenitrogenation and aromatics hydrogenation. The activity of the regenerated catalyst reaches above 95% of fresh catalyst. It is proved that ex-situ regeneration technology is effective and successful. Compared with the performance of fresh KF-848 and before the shutdown, the average temperature of the reactor using the regenerated catalyst is lower by 7~10℃; the pressure drop is improved. The N content of the product is less than 10 mg/g.