Abstract: LixK2-xTi2O5(x=0.125, 0.15, 0.2) samples were synthesized by solid-phase method using TiO2, KNO3 and LiOH·H2O as raw materials. The prepared catalysts were characterized by XRD, and their catalytic activities of soot oxidation were evaluated using TPR system under various conditions. Results showed that the structure of LixK2-xTi2O5 doped with a little Li+ was basically the same as K2Ti2O5; Li0.15K1.85Ti2O5 exhibited the highest catalytic activity among the three LixK2-xTi2O5 samples, its ignition temperature of soot was 210 ℃ and the peak temperature was 290 ℃. Furthermore, its catalytic activity of soot oxidation was significantly higher than some conventional noble metal catalyst (such as Pt-ZSM5), transition metal catalyst (such as Co,Ba,K/ZrO2) and others. Besides, its catalytic activity is higher under catalyst and soot in packed condition than in loose condition.