Abstract: Several metal salts of phosphomolybdic acid catalysts were synthesized and characterized by XRD and TGA. The catalytic performance of these prepared catalysts was studied by esterification of oleic acid and methanol reaction, and the effect of catalyst types, calcination temperature, acid/alcohol molar ratio, catalyst dosage, reaction temperature and reaction time on the conversion of oleic acid and methanol esterification was investigated. Test results showed that using SnPMo as catalyst with a dosage of 4% (based on the mass of oleic acid), under acid/alcohol molar ratio of 1:8 and refluxing at (68±1)℃ for 6 h, the conversion of esterification reached 95.4%. Moreover, this catalyst could be easily recovered and reused at least five times. The influence of various alcohols and fatty acids on the esterification was also investigated using SnPMo catalyst under the above reaction conditions. Results showed that the conversion of esterification decreased with the increase of alcohol carbon number, yet the carbon number of fatty acid had less influence on conversion.