Abstract: Using advanced software technology, an integrated management system was developed based on hydrocarbon loss theory and mathematical models. The system can calculate and forecast the benchmark loss of crude oil transportation, storage, processing, semi-finished products transit and products outgoing. It also provides many kinds of charts to help engineers analyze and evaluate the status of loss by comparing benchmark loss with statistical loss. The system has been applied in several refineries. The results show that it is helpful to decrease refinery loss.