Abstract: The blending of reformer feed with coker naphtha increases the difficulty of pre-hydrogenation operation. The main factors affecting the process were investigated in a 200mL pilot plant by response surface design. The results of response surface interaction indicated that the reaction temperature and pressure had a greater influence on the removal of impurities. The optimum process conditions for pre-hydrogenation were temperature of 287 ℃， pressure of 2.0 MPa，LHSV of 2.0 h－1，and hydrogen/oil volume ratio of 200 when the feed contained 15% coker naphtha. Using the Design expert software，the relative error between the predicted value and the experimental value of the model equation is less than 5%. The model equation can accurately simulate the sulfur and nitrogen content of the oil produced under different operating conditions and provide technical support for the optimization of industrial process conditions.

Key words: catalytic reforming, coker naphtha, process optimization, response surface methodology