Abstract: A series of composite Ni-W oxides with different ratios were synthesized. The high metal content NiW catalysts were prepared with these NiW mixed oxides as precursors and characterized by XRD, N2 adsorption-desorption, SEM and HRTEM. The competitive catalytic reactions of the catalysts were tested with a mixed model compound (naphthalene, quinoline and dibenzothiophene) to study the performance of hydrodearomatization, hydrodenitrogenation and hydrodesulfurization, respectively. The results show that the catalysts with mesoporous contain NiWO4 and WO3?0.75H2O phases, and the stacking layers of the WS2 slab on the sulfided high metal NiW are 2 to 6 with the slab length in the range of 3 to 10 nm. The reaction results reveal that high metal NiW catalyst exhibits high catalytic activity toward the conversion of quinoline and dibenzothiophene, the conversions are both more than 90%, while the conversion of naphthalene is relatively low.