Abstract: A series of W/Ni-based hydrocracking catalysts dried and calcined under various temperatures was prepared by impregnation method. The prepared catalysts were characterized by means of N2-adsorption, NH3-TPD, XRD and TPR technique; the hydrocracking performance of these catalysts was investigated using dodecane as model compound. The results showed that with the increase of calcination temperature, the specific surface area of the catalyst decreased slightly, pore size increased and pore volume was basically unchanged. The acid amount and hydrocracking activity of the catalyst both showed a tendency to ascend firstly, followed to descend with the increase of calcination temperature, and the peak value for the former and the latter was at 400 ℃ and 500 ℃, respectively. When the calcination temperature reached 600 ℃, aggregation of the metal components happened on the surface of the carrier. On the whole, catalyst calcined under suitable temperature could improve its performance, yet high temperature calcination might suppress the activity of the catalyst. Reducing the catalyst drying temperature from 200 ℃ to 120 ℃, the specific surface area of the catalyst decreased, pore size and pore volume increased, acid amount was basically unchanged and the catalyst activity enhanced.