Abstract: The 2.2 Mt/a diesel hydrotreating unit of Anqing Petrochemical Company was started-up successfully in May，2018 using ex-situ truly sulfiding technology (e-Trust) of combined hydrotreating catalysts developed by SINOPEC Research Institute of Petroleum Processing was first commercially applied in China. The catalysts were RG-1(TS) /RS-2100(TS)/RS-2200(TS). Compared with in-situ catalyst, e-Trust catalyst showed more advantages in the process of start-up. Commercial application results indicated that e-Trust shortened the start-up process efficiently for 5 days, waste water and emission gas was zero，the cost saving was more than 3 million Yuan，exhibiting its economical advantage and low environmental impact. The diesel product meets the requirements of ChinaⅤstandard.

Key words: e-trust, hydrotreating catalyst, China V standard diesel, safty and eco-friendly