Abstract: In Sinopec Qilu Company victory refinery processing of aqueous soluble drag reducing agent for crude oil sewage treatment system by A COD standard, can not discharge standards, Sinopec Qilu Company Institute by liquid chromatography, water solubility test, biochemical analysis, identified by the reason of excessive sewage, while the pipeline drag reduction agent for electric desalting simulation evaluation, screening for oil soluble drag reducing agent B and its application in industrial production, both to ensure that the crude oil transportation capacity, but also eliminate the effect of the sewage treatment system.