Abstract: A new generation of single-stage hydrocracking catalyst FC-34 has been developed to meet the domestic requirement of more clean transportation fuel and high-quality chemical feedstock. This catalyst is composed of a modified Y elite and a type of nana-amorphous silica-alumina as the main cracking components of FC-34 catalyst. DURM (Dispersion and Uniform Reactive Manufacture), a new catalyst manufacture technique, was adopted to make the catalyst with all the active components uniformly dispersed. Through the comparison of pilot plant tests, FC-34 hydro cracking catalyst demonstrates its suitable cracking activity, good hydrogenation performance, high selectivity of middle distillates and strong ring-opening ability. The overall performance in activity and middle distillate selectivity of FC-34 has reached to that of FC-14 catalyst. In addition, the BMCI of the tail oil can be greatly improved and used as an ideal feed for steam cracking to produce ethylene.