Abstract: CoMo/ USY hydrocracking catalysts were prepared using USY molecular sieve as support by using impregnation method and characterized by XRD, NH3-TPD, H2-TPR. (NH4)2S2O3 was used as a presulfidation agent. The performance of coal tar hydrocracking of catalysts prepared with different Mo loading was investigated by orthogonal test in a continuous flow fixed-bed reactor. The results indicate that the catalyst with 12% Mo is the best. The yield of fuel oil reached 86% under the reaction conditions of a temperature of 385 ℃, a pressure of 9 MPa, a WHSV of 0.6 h-1, and a H2/oil ratio of 1 000.