Abstract: A six-lumped high pressure hydrocracking kinetic model based on VGO hydrocracking experiment data of catalyst A was established to predict product yields. Based on the actual hydrocracking product cutting scheme, the oils (feedstock and product oils) were divided into six lumps according to the fixed distillation range: vacuum gas oil and unconverted bottom oil (>360 ℃), diesel fraction (290-360 ℃), kerosene fraction (175-290 ℃), heavy naphtha fraction (65-175 ℃), light naphtha fraction (<65 ℃) and refinery gas (C4-). The parameters of the lumped kinetic model were regressed from the hydrocracking experiment data by nonlinear least squares algorithm in Matlab 2011b. Partial reaction pathways among six lumps were ignored after statistics analysis. The results show that the calculation is in good agreement with the experimental product yields with the largest deviation of 1.8% which meet the industrial demands.